Bio-Connect

HNMT Polyclonal Antibody

Research Use Only
RD82661A
Reddot Biotech
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetHNMT
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    HNMT Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoFluorescence, Western Blot
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3176
  • Target name
    HNMT
  • Target description
    histamine N-methyltransferase
  • Target synonyms
    histamine N-methyltransferase; HMT; HNMT-S1; HNMT-S2; MRT51
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203