Homoharringtonine (CGX-635) [26833-87-4]
S9015
CAS Number26833-87-4
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameHomoharringtonine (CGX-635) [26833-87-4]
- Delivery Days Customer9
- CAS Number26833-87-4
- CertificationResearch Use Only
- Scientific DescriptionHomoharringtonine (CGX-635, Omacetaxine mepesuccinate, HHT, Myelostat, NSC 141633), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.
- UNSPSC12352200