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HPGDS inhibitor 3
T61250
CAS Number2255311-93-2
Product group Chemicals
Molecular Weight353.46
Overview
- SupplierTargetMol Chemicals
- Product NameHPGDS inhibitor 3
- Delivery Days Customer72
- CAS Number2255311-93-2
- Category SupplierChemical
- Chemical NameHPGDS inhibitor 3
- Molecular FormulaC21H27N3O2
- Molecular Weight353.46
- Scientific DescriptionHPGDS inhibitor 3 is a powerful oral compound that selectively inhibits the hematopoietic prostaglandin D synthase (H-PGDS). With an IC50 value of 9.4 nM and EC50 of 42 nM, it demonstrates high potency in peripherally restricting H-PGDS. Moreover, HPGDS inhibitor 3 exhibits excellent selectivity with no associated central nervous system toxicity. This compound also possesses favorable pharmacokinetic properties in mouse, rat, and dog models. Additionally, HPGDS inhibitor 3 displays noteworthy anti-inflammatory activity [1].
- Shelf life instruction3 years
- SMILESC(N[C@@H]1CC[C@@H](C(C)(C)O)CC1)(=O)C2=CC3=C(N=C(C=C3)C4CC4)N=C2
- Storage Instruction-20°
- UNSPSC12352200