HPK1-IN-16

MedChem Express

HPK1-IN-16

10

Research Use Only

C28H27FN4O

454.54

HPK1-IN-16 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-16 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2019051199A1, compound 39)[1].

N#CC1=C(C2=C(C=C(CNC)C=C2C)F)C=C3C(C4=CC=C(C5CCOCC5)C=C4)=NNC3=C1

12352200