HPK1-IN-33

MedChem Express

HPK1-IN-33

10

Research Use Only

C18H16ClFN6

370.81

HPK1-IN-33 (compound 21) is a potent Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor with a Ki value of 1.7 nM. HPK1-IN-33 inhibits the produce of IL-2 with EC50s of 286, >10000 nM in Jurkat WT and Jurkat HPK1 KO cells, respectively[1].

N#CC1=CC(C2=C(NC3=NC=NC(N4CC[C@H]([C@H](C4)N)F)=C32)Cl)=CC=C1

12352200