CgoaEGY7Lk6EVmtKAAAAAGHgdfA960.png
CgoaEGY7Lk6EVmtKAAAAAGHgdfA960.png
HPK1-IN-33
T73149
CAS Number2920000-86-6
Product group Chemicals
Molecular Weight370.81
Overview
- SupplierTargetMol Chemicals
- Product NameHPK1-IN-33
- Delivery Days Customer86
- CAS Number2920000-86-6
- Category SupplierChemical
- Chemical NameHPK1-IN-33
- Molecular FormulaC18H16ClFN6
- Molecular Weight370.81
- Scientific DescriptionHPK1-IN-33 (compound 21), a Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor, exhibits a high potency with a K_i of 1.7 nM. It effectively inhibits IL-2 production, demonstrating EC_50 values of 286 nM in Jurkat WT cells and >10000 nM in Jurkat HPK1 KO cells [1].
- Shelf life instruction3 years
- SMILESN#Cc1cccc(-c2c(Cl)[nH]c3ncnc(N4CC[C@@H](F)[C@@H](N)C4)c23)c1
- Storage Instruction-20°
- UNSPSC12352200