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HPK1-IN-4

HPK1-IN-4

T40350
TargetMol Chemicals
CAS Number2739844-28-9
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Product group Chemicals
Molecular Weight434.49
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    HPK1-IN-4
  • Delivery Days Customer
    4
  • CAS Number
    2739844-28-9
  • Category Supplier
    Chemical
  • Chemical Name
    HPK1-IN-4
  • Molecular Formula
    C23H26N6O3
  • Molecular Weight
    434.49
  • Scientific Description
    HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.
  • Shelf life instruction
    3 years
  • SMILES
    N(C1=C(OC)C=C2C(=C1)CN(C)CC2)C=3N=C(NC4=C(CO)C=CC=C4)C(C(N)=O)=CN3
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Brandon A Vara, et al. Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds. ACS Med Chem Lett. 2021 ; 12(4):653-661.
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