HRG Polyclonal Antibody

Reddot Biotech

HRG Polyclonal Antibody

5

Western Blot, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

HRG

histidine rich glycoprotein

histidine-proline-rich glycoprotein; histidine-rich glycoprotein; HPRG; HRGP; THPH11

Rabbit

IgG

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the proteins effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Mouse, Rat

-20°C

12352203