HS-243

MedChem Express

HS-243

10

Research Use Only

99.88

C17H16N4O3

324.33

HS-243 is a potent and selective IRAK-4 and IRAK-1 inhibitor, with IC50 values of 20 and 24 nM. HS-243 shows minimal TAK1 (transforming growth factor beta-activated kinase 1) inhibition activity, with a IC50 of 0.5 microM. HS-243 shows anti-inflammatory and anticancer activity[1].

O=C(NC1=NC2=CC=CC=C2N1CCC)C3=CC=CC([N+]([O-])=O)=C3

-20°C,2°C to 8°C

12352200