HSD17B13-IN-16 [2758802-09-2]

TargetMol Chemicals

HSD17B13-IN-16 [2758802-09-2]

16

Research Use Only

C20H17ClN2O4S

416.88

HSD17B13-IN-16 (compound 8) serves as a potent inhibitor of hydroxysteroid 17beta-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of <0.1 microM and <1 microM when using estradiol and Leukotriene B3 as substrates, respectively. The compound is notably significant in the treatment of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].

C(NCC1=C(OC)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(Cl)=C(O)C=C3)C=CS2

-20°C

51202000