HSD17B13-IN-36 [2730027-86-6]

TargetMol Chemicals

HSD17B13-IN-36 [2730027-86-6]

16

Research Use Only

C20H17F2N3O4S

433.43

HSD17B13-IN-36 (compound 116) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of <0.1 microM with estradiol as substrates. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including NASH (nonalcoholic steatohepatitis) [1].

O(C1=NC(=NC=C1)C2=CC=C(C=C2)N3CCS(=O)(=O)CC3)C4=C(F)C(O)=C(F)C=C4

-20°C

51202000