HSD17B13-IN-51 [2770246-75-6]

TargetMol Chemicals

HSD17B13-IN-51 [2770246-75-6]

16

Research Use Only

C22H13Cl2F3N4O3

509.26

HSD17B13-IN-51 (Compound 82), an inhibitor targeting hydroxysteroid 17beta-dehydrogenase 13 (HSD17B13), exhibits potent activity with an IC50 value of ≤ 0.1 microM against estradiol. This compound is useful in researching various conditions including liver, metabolic, and cardiovascular diseases-specifically NAFLD, NASH, and drug-induced liver injury (DILI) [1].

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(C(F)(F)F)N=CC=C4)C3=O)=CC=C2

-20°C

51202000