HSD17B13-IN-66 [2770247-37-3]

TargetMol Chemicals

HSD17B13-IN-66 [2770247-37-3]

16

Research Use Only

C24H17Cl2F3N4O3

537.32

HSD17B13-IN-66 (Compound 146), an inhibitor of hydroxysteroid 17beta-dehydrogenase 13 (HSD17B13), shows a potent IC 50 value of ≤ 0.1 microM for estradiol. This compound is primarily utilized in research pertaining to liver diseases, metabolic disorders, and cardiovascular conditions, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI) [1].

N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=C(C)N(CC4=C(C(F)(F)F)C=CC=N4)C3=O)=C(C)C=C2

-20°C

51202000