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Hsp90-Cdc37-IN-1 [2227303-22-0]

Research Use Only
T13725
TargetMol Chemicals
CAS Number2227303-22-0
Product group Chemicals
Molecular Weight748.99
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Hsp90-Cdc37-IN-1 [2227303-22-0]
  • Delivery Days Customer
    72
  • CAS Number
    2227303-22-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Hsp90-Cdc37-IN-1
  • Molecular Formula
    C43H57FN2O6S
  • Molecular Weight
    748.99
  • Scientific Description
    Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibits cell migration and reverses drug resistance.
  • Shelf life instruction
    3 years
  • SMILES
    C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](OC(CCC(NC=4SC=5C(N4)=CC=C(F)C5)=O)=O)CC3)[H])(C(=O)C=C6[C@@]2(C)CC[C@]7(C)[C@]6(C[C@](C(OCC)=O)(C)CC7)[H])[H]
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Jin L, et al. Discovery of 18bèta-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance. Bioorg Med Chem. 2018 May 1;26(8):1759-1775.
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