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Hsp90-Cdc37-IN-1 [2227303-22-0]
T13725
Overview
- SupplierTargetMol Chemicals
- Product NameHsp90-Cdc37-IN-1 [2227303-22-0]
- Delivery Days Customer72
- CAS Number2227303-22-0
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameHsp90-Cdc37-IN-1
- Molecular FormulaC43H57FN2O6S
- Molecular Weight748.99
- Scientific DescriptionHsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibits cell migration and reverses drug resistance.
- Shelf life instruction3 years
- SMILESC[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](OC(CCC(NC=4SC=5C(N4)=CC=C(F)C5)=O)=O)CC3)[H])(C(=O)C=C6[C@@]2(C)CC[C@]7(C)[C@]6(C[C@](C(OCC)=O)(C)CC7)[H])[H]
- Storage Instruction-20°C
- UNSPSC51202000
References
- Jin L, et al. Discovery of 18bèta-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance. Bioorg Med Chem. 2018 May 1;26(8):1759-1775.Read more