Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HTRA3 Polyclonal Antibody at dilution 1:45
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HTRA3 Polyclonal Antibody at dilution 1:45
HTRA3 Polyclonal Antibody
E-AB-13006
Product group Antibodies
Overview
- SupplierElabscience
- Product NameHTRA3 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.2mg/ml
- Scientific DescriptionHtrA3, also known as PRSP (pregnancy-related serine protease), is a 453 amino acid secreted protein that contains one PDZ domain, one Kazal-like domain and one IGFBP N-terminal domain. Widely expressed with particularly high expression in ovary, heart, placenta and bladder, HtrA3 functions as a probable serine protease that is thought to play an important role in placental development. HtrA3 is downregulated in ovarian tumors, suggesting an alternative role in tumor suppression. HtrA3 exists as two alternatively spliced isoforms, designated short and long. The gene encoding HtrA3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
- UNSPSC12352203