Human AIMP1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human AIMP1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag
EM2-H5142
Product group Proteins / Signaling Molecules
Overview
- SupplierACRObiosystems
- Product NameHuman AIMP1 / EMAP2 / SCYE1 Protein, His Tag
- Delivery Days Customer4
- Category SupplierCytokines&Growth Factors
- CertificationResearch Use Only
- Estimated Purity95%
- FormatPowder
- Scientific DescriptionCharacteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 35.2 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE). Description: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is also known as multisynthase complex auxiliary component p43 and endothelial monocyte-activating polypeptide II (EMAP-II). AIMP1 is a cytokine that may be induced by apoptosis and is also released from professional antigen-presenting cells such as dendritic cells. The release of AIMP1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 binds tRNA and stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. This protein possesses inflammatory cytokine activity. Also, AIMP1 negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.
- Shelf life instruction● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- SourceHuman AIMP1, His Tag (EM2-H5142) is expressed from E. coli cells. It contains AA Ala 2 - Lys 312 (Accession # Q12904-1).
- Storage Instruction-20℃
- UNSPSC12352202