Human BACE1 / BACE Protein (Recombinant Fc) (Met1-Thr457)

LifeSpan BioSciences

Human BACE1 / BACE Protein (Recombinant Fc) (Met1-Thr457)

14

Research Use Only

>90%

The recombinant human BACE1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 674 amino acids and has a calculated molecular mass of 75 kDa. As a result of glycosylation, the rhBACE1/Fc monomer migrates as an approximately 100-105 kDa protein in SDS-PAGE under reducing conditions. A DNA sequence encoding the extracellular domain (Met 1-Thr 457) of human BACE1 (NP_036236.1) was expressed as a secreted chimeric protein with the C-terminal fused Fc region of human IgG1.

-80°C

12352202