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Human beta-Amyloid (1 - 42) ELISA Kit

Research Use Only
ARG81143
Arigo Biolaboratories
Product group Assays
Price on request
Packing Size
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    Human beta-Amyloid (1 - 42) ELISA Kit
  • Delivery Days Customer
    23
  • Applications
    ELISA
  • Assay Sensitivity
    0.29 pg/ml
  • Assay Specificity
    Human Abeta (1-42) 100.0%, Human Abeta (1-40) ≦0.1 %, Human Abeta (1-43) <0.8 %
  • Assay Time
    Overnight
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116133