Human CCL4 / MIP-1 Beta Protein (Recombinant) (Ala24-Asn92)

LifeSpan BioSciences

Human CCL4 / MIP-1 Beta Protein (Recombinant) (Ala24-Asn92)

23

Research Use Only

>95%

Macrophage inflammatory protein 1 beta (MIP-1Beta), also known as Chemokine (C-C motif) ligand 4 (CCL4), is a small cytokine belonging to the CC chemokine family. It is a chemo attractant for natural killer cells, monocytes and a variety of other immune cells. MIP-1Beta is a major HIV-suppressive factor produced by CD8+ T cells. Perforin-low memory CD8+ T cells are the most common T-cells that normally synthesize MIP-1-beta in humans. MIP-1Beta has been shown to interact with CCL3. It can signal through the CCR5 receptor.Recombinant MIP-1 beta/CCL4 produced in CHO is a polypeptide chain containing 69 amino acids. A fully biologically active molecule, rhMIP-1 beta/CCL4 has a molecular mass of 10-19 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.

2°C to 8°C,-20°C,-80°C

12352202