Human CD40 Ligand/TNFSF5 Protein (CDL-HE14L)

KACTUS

Human CD40 Ligand/TNFSF5 Protein (CDL-HE14L)

9

Research Use Only

>95%

CD40 ligand

CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, alpha5beta1 integrin and alphaIIbbeta3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.

-80°C

12352202