Human CD47, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human CD47 Protein, His Tag (MALS verified)
CD7-H5227
Overview
- SupplierACRObiosystems
- Product NameHuman CD47 Protein, His Tag (MALS verified)
- Delivery Days Customer4
- Category SupplierImmune Checkpoint Proteins
- CertificationResearch Use Only
- ConjugateUnconjugated
- Estimated Purity95%
- FormatPowder
- Molecular Weight15.6 kDa
- Scientific DescriptionCharacteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.6 kDa. The protein migrates as 33-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Description: Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
- Shelf life instruction● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- SourceHuman CD47, His Tag (CD7-H5227) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Pro 139 (Accession # Q08722-3).
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteC-10×His. HEK293. Gln 19 - Pro 139
- Storage Instruction-20℃
- UNSPSC12352202