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3 microg of GTX66975-pro Human DUSP3 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
3 microg of GTX66975-pro Human DUSP3 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
3 microg of GTX66975-pro Human DUSP3 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain

Human DUSP3 protein (active)

Research Use Only
GTX66975-PRO
GeneTex
Product group Molecular Biology
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Human DUSP3 protein (active)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Conjugate
    Unconjugated
  • Scientific Description
    The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    41116133