Human EGF protein (active)

GeneTex

Human EGF protein (active)

9

The determined ED50 is ≤ 0.1 ng/mL, which corresponds to a specific activity of ≥ 1 x 107 units/mg and is comparable to similar commercial products. The biological activity of this recombinant human EGF protein was analyzed using the BALB/c 3T3 Clone A31 mouse embryonic fibroblast cell proliferation assay (Rubin, J.S. et al. (1991)).

Functional Assay

Research Use Only

Unconjugated

Pro-epidermal growth factor

This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

-20°C,-80°C,2°C to 8°C

12352202