Human ERBB3 / HER3 Protein (Recombinant Fc) (Met1-Thr643)

LifeSpan BioSciences

Human ERBB3 / HER3 Protein (Recombinant Fc) (Met1-Thr643)

14

Research Use Only

>90%

The mature recombinant human ErbB3/Fc chimera is a disulfide-linked homodimeric protein after the removal of signal peptide. The monomer consists of 862 amino acids and has a calculated molecular mass of 95.4 kDa. As a result of glycosylation, the recombinant monomer migrates as an approximately 130-140 kDa protein in SDS-PAGE under reducing conditions. A DNA sequence encoding the extracellular domain (Met 1-Thr 643) of human ErbB3 (NP_001973.2) precursor was expressed with the C-terminal fused Fc region of human IgG1.

-80°C

12352202