Human FOLR4/Juno Protein (FOL-HM1R4)

KACTUS

Human FOLR4/Juno Protein (FOL-HM1R4)

9

>95%

Lyophilized

Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Junos presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor.

-20°C or -80°C,-80°C

12352202