3 microg of GTX67039-pro Human GSTM5 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
Human GSTM5 protein (active)
GTX67039-PRO
Product group Molecular Biology
Overview
- SupplierGeneTex
- Product NameHuman GSTM5 protein (active)
- Delivery Days Customer9
- CertificationResearch Use Only
- ConjugateUnconjugated
- Scientific DescriptionCytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individuals susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC41116133