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ProductsBack/Human HLA-A02:01&B2M&CMVpp65 (NLVPMVATV) Tetramer Protein (MHC-HE013T)

Human HLA-A02:01&B2M&CMVpp65 (NLVPMVATV) Tetramer Protein (MHC-HE013T)

MHC-HE013T
KACTUS
Protein IDP61769
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Human HLA-A02:01&B2M&CMVpp65 (NLVPMVATV) Tetramer Protein (MHC-HE013T)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Protein IDP61769
  • Protein Name
    Beta-2-microglobulin
  • Scientific Description
    Human cytomegalovirus (CMV), a beta-herpes virus with a double-stranded DNA, infects a wide variety of cells and establishes latency in the host. CMVpp65, a tegument protein of the herpes virus CMV, is the main viral antigen found in peripheral blood mononuclear cells (PBMCs) after viral infection and may activate cell-mediated immunity, accounting for 70-90% of the cytotoxic CD8+ T cells (CTLs) response to CMV. Among the pp65-derived CTL epitope peptides, the 9-mer peptide 495NLVPMVATV503 (CMVpp65 495-503 peptide) is the most immunogenic T cell epitope predominantly displayed on HLA-A*02:01, the most common MHC-I allele in the population.
  • Storage Instruction
    -80°C
  • UNSPSC
    12352202