Human HLA-A02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein (MHC-HM416)
MHC-HM416
Protein IDP61769
Product group Proteins / Signaling Molecules
Overview
- SupplierKACTUS
- Product NameHuman HLA-A02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein (MHC-HM416)
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity>95%
- Protein IDP61769
- Protein NameBeta-2-microglobulin
- Scientific Descriptionp53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202