Human HLA-DRB1 Protein (Recombinant His)
![Research Use Only](static/images/certificates/ruo.jpg)
LS-G2798
Product group Proteins / Signaling Molecules
Overview
- SupplierLifeSpan BioSciences
- Product NameHuman HLA-DRB1 Protein (Recombinant His)
- Delivery Days Customer23
- CertificationResearch Use Only
- Concentration1 mg/ml
- Estimated Purity>85%
- Scientific DescriptionHLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Recombinant human HLA-DRB1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202