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Human IgG1 kappa isotype control

GTX16193
GeneTex
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    Human IgG1 kappa isotype control
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    0.50 mg/ml
  • Conjugate
    Unconjugated
  • Host
    Human
  • Isotype
    IgG1
  • Scientific Description
    Inclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific background binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Identification and characterization of blocking nanobodies against human CD70.
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  • A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells. Ko YA et al., 2021 Aug, PLoS Pathog
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  • Monocyte TREM-1 Levels Associate With Anti-TNF Responsiveness in IBD Through Autophagy and Fcgamma-Receptor Signaling Pathways. Prins MM et al., 2021, Front Immunol
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  • The Role of Microglia and Peripheral Monocytes in Retinal Damage after Corneal Chemical Injury. Paschalis EI et al., 2018 Jul, Am J Pathol
    Read more