Human IgG1 kappa isotype control
GTX16193
Overview
- SupplierGeneTex
- Product NameHuman IgG1 kappa isotype control
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- HostHuman
- IsotypeIgG1
- Scientific DescriptionInclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific background binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Identification and characterization of blocking nanobodies against human CD70.Read more
- A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells. Ko YA et al., 2021 Aug, PLoS PathogRead more
- Monocyte TREM-1 Levels Associate With Anti-TNF Responsiveness in IBD Through Autophagy and Fcgamma-Receptor Signaling Pathways. Prins MM et al., 2021, Front ImmunolRead more
- The Role of Microglia and Peripheral Monocytes in Retinal Damage after Corneal Chemical Injury. Paschalis EI et al., 2018 Jul, Am J PatholRead more