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Human LILRA3/CD85e Protein (LIL-HM4A3)

LIL-HM4A3
KACTUS
Protein IDQ8N6C8
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Human LILRA3/CD85e Protein (LIL-HM4A3)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Protein IDQ8N6C8
  • Protein Name
    Leukocyte immunoglobulin-like receptor subfamily A member 3
  • Scientific Description
    Human LILRA3, also known as Leukocyte Ig-like receptor 4 (LIR-4), CD85 antigen-like family member E, Immunogobulin-like transcript 6 (ILT-6) and monocyte inhibitory receptor HM43/HM31, is a 70 kD Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LILRA3 is 416 amino acids (aa) in length and contains four C2-type Ig-like domains. Unlike other LILR family members, LILRA3 is actively secreted.LILRA3 acts as soluble receptor for class I MHC antigens. LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202