Human NPC2 Protein (NPC-HM102)

KACTUS

Human NPC2 Protein (NPC-HM102)

9

Research Use Only

>95%

The Niemann Pick type C (NPC) proteins, NPC1 and NPC2, are involved in the lysosomal storage disease, NPC disease. The formation of a NPC1-NPC2 protein-protein complex is believed to be necessary for the transfer of cholesterol and lipids out of the late endosomal (LE)/lysosomal (Lys) compartments. Mutations in either NPC1 or NPC2 can lead to an accumulation of cholesterol and lipids in the LE/Lys, the primary phenotype of the NPC disease.

-20°C or -80°C,-80°C

12352202