GTX01328-pro Image
Human p63 protein, GST and His tag
GTX01328-PRO100
Overview
- SupplierGeneTex
- Product NameHuman p63 protein, GST and His tag
- Delivery Days Customer9
- Category Supplierprotein
- CertificationResearch Use Only
- Protein IDQ9H3D4
- Protein NameTumor protein 63
- Scientific DescriptionThis gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016]
- Storage Instruction-20°C
- UNSPSC12352202