Human POLL / DNA Polymerase Lambda Protein (Recombinant His)

LifeSpan BioSciences

Human POLL / DNA Polymerase Lambda Protein (Recombinant His)

23

Research Use Only

0.5 mg/ml

>90%

DNA polymerase lambda, also known as POLL, is a DNA polymerase involved in base excision repair (BER). POLL is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. In addition, POLL may play a role in the mutagenic bypass of T-T dimers. Pol lambda possesses terminal transferase and 5-deoxyribose-5-phosphate lyase activity. These activities have been found to be coordinated by PCNA and replication protein A. Recombinant human POLL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

2°C to 8°C,-20°C or -80°C

12352202