Human PSME3 / PA28g Protein, His Tag

ACRObiosystems

Human PSME3 / PA28g Protein, His Tag

4

Other Recombinant Proteins

Research Use Only

Unconjugated

95%

Powder

30.3 kDa

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 30.3 kDa. The protein migrates as 28-33 kDa under reducing (R) condition (SDS-PAGE). Description: Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation.

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Human PSME3, His Tag (PS3-H5142) is expressed from E. coli cells. It contains AA Ala 2 - Tyr 254 (Accession # P61289-1).

Human

Human

N-6×His. E. coli. Ala 2 - Tyr 254

-20℃

12352202