Human recombinant Galectin-12 protein, AF

Boster Bio

Human recombinant Galectin-12 protein, AF

9

Other Application

Research Use Only

>98%

Galectin-12

Galectin-12 (Gal-12) is a lectin family member and is one of the tandem repeat-type galectins containing two carbohydrate recognition domains (CRD) connected by a linker region in a single peptide chain. The CRD is responsible for beta-galactoside binding and is required to interact with the VPS13C protein. It has been reported that galectin-12 is presented in the adipose tissue but also expressed in macrophages and other leukocytes. Galectin-12 participates in many biological activities including cell cycle regulation, apoptosis, and cell differentiation. Moreover, galectin-12 has emerged as a crucial factor in driving the macrophage to M1 polarization, leading to inflammation and reducing insulin sensitivity in adipocytes.

E.coli

-20°C,-20°C or -80°C,2°C to 8°C

12352202