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Human SHH / Sonic Hedgehog Protein (Recombinant)

LS-G27150
LifeSpan BioSciences
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    LifeSpan BioSciences
  • Product Name
    Human SHH / Sonic Hedgehog Protein (Recombinant)
  • Delivery Days Customer
    23
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    Sonic Hedgehog (Shh) is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. In mammal, there are three related Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh). They share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical). Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body.Recombinant human Sonic Hedgehog (C24II) (rhShh) produced in E. coli is a single non-glycosylated polypeptide chain containing 175 amino acids. A fully biologically active molecule, rhShh has a molecular mass of 19.7 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
  • Storage Instruction
    -20°C,-80°C,2°C to 8°C
  • UNSPSC
    12352202