Bio-Connect

Human TNFR2/CD120b/TNFRSF1B Protein (TNF-HM1R2)

TNF-HM1R2
KACTUS
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Human TNFR2/CD120b/TNFRSF1B Protein (TNF-HM1R2)
  • Delivery Days Customer
    9
  • Estimated Purity
    >95%
  • Scientific Description
    Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202