Human TNFRSF12A / TWEAK Receptor Protein (Recombinant)
LS-G131449
Product group Proteins / Signaling Molecules
Overview
- SupplierLifeSpan BioSciences
- Product NameHuman TNFRSF12A / TWEAK Receptor Protein (Recombinant)
- Delivery Days Customer14
- CertificationResearch Use Only
- Estimated Purity>95%
- Scientific DescriptionTumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is the receptor for TNFSD12/TWEAK and is the smallest member of the TNF receptor superfamily. It is composed of a signal peptide, an extracellular domain, a membrane-anchoring domain, and a cytoplasmic death domain, which can activate a cells apoptotic mechanisms. It also promotes endothelial cell proliferation and angiogenesis, and modulates cellular adhesion to matrix proteins. TNFRSF12A expression can be found in the spleen, thymus, small intestine, and colon, and can be activated by membrane-anchored or soluble versions of TWEAK.
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352202