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Humanin [330936-69-1]

Humanin [330936-69-1]

T76033
TargetMol Chemicals
CAS Number330936-69-1
Product group Chemicals
Molecular Weight2687.23
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Humanin [330936-69-1]
  • Delivery Days Customer
    999
  • CAS Number
    330936-69-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Humanin
  • Molecular Formula
    C119H204N34O32S2
  • Molecular Weight
    2687.23
  • Scientific Description
    Humanin, a 24-amino acid anti-apoptotic peptide and Bax inhibitor, prevents Bax translocation from the cytosol to mitochondria and obstructs its activation. This mitochondria-associated peptide has neuroprotective properties against Alzheimers Disease (AD)-related neurotoxicity and enhances insulin sensitivity in animals, linking it to aging processes [1] [2]. An analogue named HNG, with serine at position 14 substituted for glycine, has been developed [2].
  • Shelf life instruction
    3 years
  • SMILES
    C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC(CNC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@H](CCSC)N)=O)C)=O)CCC2)CCCNC(=N)N)=O)=O)=O)CO)=O)CS)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)[C@@H](C)O)=O)CO)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)CC(C)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N[C@H](C(O)=O)C)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)[C@H](C)C)=O)CCC3
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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