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Huwentoxin- IV

Research Use Only
PCB-4455-s
Biosynth
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    Biosynth
  • Product Name
    Huwentoxin- IV
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Scientific Description
    HWTX-IV Chinese Bird Spider, Ornithoctonus huwena) Glu- Cys- Leu- Glu- Ile- Phe- Lys- Ala- Cys- Asn- Pro- Ser- Asn- Asp- Gln- Cys- Cys- Lys- Ser- Ser- Lys- Leu- Val- Cys- Ser- Arg- Lys- Thr- Arg- Trp- Cys- Lys- Tyr- Gln- Ile- NH2 (Disulfide bonds between Cys2- Cys17, Cys9- Cys24, and Cys16- Cys31) (Trifluoroacetate Form) (M.W. 4106.80) C174H278N52O51S6 Neuronal Tetrodotoxin-Sensitive Na+-Channel Blocker References: K. Peng, Q. Shu, Z. Liu, and S. Liang,J. Biol. Chem.,277,47564 (2002).(Original) J. Diao, Y. Lin, J. Tang, and S. Liang,Toxicon,42,715 (2003).(cDNA Seq) Y. Xiao, J.-P. Bingham, W. Zhu, E. Moczydlowski, S. Liang, and T.R. Cummins,J. Biol. Chem.,283,27300 (2008).(Pharmacol.) Y. Xiao, X. Luo, F. Kuang, M. Deng, M. Wang, X. Zeng, and S. Liang,Toxicon,51,230 (2008).(Pharmacol.)
  • Source
    Chinese Bird Spider, Ornithoct
  • UNSPSC
    12352202