Hydrochlorothiazide-15N2,13C,d2
HY-B0252S3
Overview
- SupplierMedChem Express
- Product NameHydrochlorothiazide-15N2,13C,d2
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC6 13CH6D2ClN 15N2O4S2
- Molecular Weight302.73
- Scientific DescriptionHydrochlorothiazide-15N2,13C,d2 is 15N and deuterated labeled Hydrochlorothiazide (HY-B0252). Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-beta/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].
- SMILESO=S(C1=C(Cl)C=C(C2=C1)N[13C]([2H])([2H])[15NH]S2(=O)=O)([15NH2])=O
- UNSPSC12352200