Hydroxybupropion

MedChem Express

Hydroxybupropion

9

99.91

C13H18ClNO2

255.74

Hydroxybupropion is the major active metabolite of Bupropion. Hydroxybupropion is metabolized by CYP2B6. Bupropion is an atypical antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake with an IC 50 value of 1.7 microM. Hydroxybupropion is also a nACh receptor antagonist [1] .

CC(NC(C)(C)CO)C(C1=CC=CC(Cl)=C1)=O

-20°C,2°C to 8°C

12352200