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Hypidone (hydrochloride)

HY-100769
MedChem Express
CAS Number1339058-04-6
Product group Chemicals
Estimated Purity99.73
Molecular Weight334.84
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Hypidone (hydrochloride) [1339058-04-6]
  • Delivery Days Customer
    10
  • CAS Number
    1339058-04-6
  • Estimated Purity
    99.73
  • Molecular Formula
    C18H23ClN2O2
  • Molecular Weight
    334.84
  • Scientific Description
    Hypidone hydrochloride (YL0919) is an orally active antidepressant agent with dual activity as a highly seletive 5-HT uptake blocker and an effective 5-HT 1A ?receptor agonist ( K i =0.19 nM). Hypidone hydrochloride inhibits the uptake of [ 3 H]-5-HT into rat cerebral cortical synaptosomes and HEK293 cells with IC 50 s of 1.78 nM and 1.93 nM, respectively. Hypidone hydrochloride shows remarkable antidepressant effects in animal models and has the poential for the investigation of depressive disorder [1] .
  • SMILES
    O=C1C=CC=CN1CC2(O)CCN(CC3=CC=CC=C3)CC2.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200