I-138 [2098211-50-6]

TargetMol Chemicals

I-138 [2098211-50-6]

10

Chemical

Research Use Only

I-138

99.41%

C26H23F3N6O

492.5

I-138 is an orally active and potent reversible inhibitor of USP1-UAF1.I-138 induces mono-ubiquitination of FANCD2 and PCNA and inhibits USP1 auto-cleavage in cells.

3 years

C(N1C=2C(NC1=O)=CN=C(N2)C3=C(C(C)C)C=CC=C3)C4=CC=C(C=C4)C5=NC(C(F)(F)F)=CN5C

-20°C

12352200