I-BET151 (dihydrochloride)

MedChem Express

I-BET151 (dihydrochloride) [1883545-47-8]

5

1883545-47-8

Research Use Only

C23H23Cl2N5O3

488.37

I-BET151 dihydrochloride (GSK1210151A dihydrochloride) is a BET bromodomain inhibitor which inhibits BRD4 , BRD2 , and BRD3 with pIC 50 of 6.1, 6.3, and 6.6, respectively [1] [2] .

[H]Cl.[H]Cl.C[C@@H](N1C(C(C=C(OC)C(C2=C(C)ON=C2C)=C3)=C3N=C4)=C4NC1=O)C5=CC=CC=N5

12352200