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I-BET151 (GSK1210151A)

I-BET151 (GSK1210151A)

Research Use Only
27629-3
BPS Bioscience
CAS Number1300031-49-5
Product group Chemicals
Molecular Weight415.4 Da
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    I-BET151 (GSK1210151A)
  • Delivery Days Customer
    7
  • CAS Number
    1300031-49-5
  • Certification
    Research Use Only
  • Molecular Formula
    C23H21N5O3
  • Molecular Weight
    415.4 Da
  • Scientific Description
    I-BET151(GSK1210151A) is a BET bromodomain inhibitor. I-BET151 displays potent binding affinity to BRD2, BRD3 and BRD4 with Kd of 0.02-0.1 microM. I-BET151 (0.5 or 5 microM) inhibits the binding of BETs (BRD2, BRD3, BRD4, and BRD9) but not the binding of 23 other bromodomain proteins. I-BET151 also blocks recruitment of BET to chromatin.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200