I-OMe-Tyrphostin AG 538
HY-135680
CAS Number1094048-77-7
Product group Chemicals
Estimated Purity98.03
Molecular Weight437.19
Overview
- SupplierMedChem Express
- Product NameI-OMe-Tyrphostin AG 538 [1094048-77-7]
- Delivery Days Customer10
- CAS Number1094048-77-7
- CertificationResearch Use Only
- Estimated Purity98.03
- Molecular FormulaC17H12INO5
- Molecular Weight437.19
- Scientific DescriptionI-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells.?I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase alpha (PI5P4Kalpha) , with an IC 50 ?of 1 microM [1] .
- SMILESN#C/C(C(C1=CC=C(O)C(O)=C1)=O)=C\C2=CC(OC)=C(O)C(I)=C2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200