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I-OMe-Tyrphostin AG 538

HY-135680
MedChem Express
CAS Number1094048-77-7
Product group Chemicals
Estimated Purity98.03
Molecular Weight437.19
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Overview

  • Supplier
    MedChem Express
  • Product Name
    I-OMe-Tyrphostin AG 538 [1094048-77-7]
  • Delivery Days Customer
    10
  • CAS Number
    1094048-77-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.03
  • Molecular Formula
    C17H12INO5
  • Molecular Weight
    437.19
  • Scientific Description
    I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells.?I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase alpha (PI5P4Kalpha) , with an IC 50 ?of 1 microM [1] .
  • SMILES
    N#C/C(C(C1=CC=C(O)C(O)=C1)=O)=C\C2=CC(OC)=C(O)C(I)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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