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ProductsBack/Iba1 antibody [GT10312]

Iba1 antibody [GT10312]

GTX632426
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetAIF1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Iba1 antibody [GT10312]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT10312
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID199
  • Target name
    AIF1
  • Target description
    allograft inflammatory factor 1
  • Target synonyms
    AIF-1; allograft inflammatory factor 1; IBA1; interferon gamma responsive transcript; ionized calcium-binding adapter molecule 1; IRT1; IRT-1; protein G1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP55008
  • Protein Name
    Allograft inflammatory factor 1
  • Scientific Description
    This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Inhibition of Dectin-1 Alleviates Neuroinflammatory Injury by Attenuating NLRP3 Inflammasome-Mediated Pyroptosis After Intracerebral Hemorrhage in Mice: Preliminary Study Results. Ding Z et al., 2022, J Inflamm Res
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  • Paclitaxel induces cognitive impairment via necroptosis, decreased synaptic plasticity and M1 polarisation of microglia. Tang M et al., 2022 Dec, Pharm Biol
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  • Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage. Fei X et al., 2022 Mar 14, J Neuroinflammation
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  • The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinsons disease. Zhang C et al., 2021 Nov, Redox Biol
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  • LncRNA 4344 promotes NLRP3-related neuroinflammation and cognitive impairment by targeting miR-138-5p. Feng X et al., 2021 Nov, Brain Behav Immun
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  • Fiber scaffold bioartificial liver therapy relieves acute liver failure and extrahepatic organ injury in pigs. Weng J et al., 2021, Theranostics
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  • Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS. Ciervo Y et al., 2021 Jun 11, Mol Ther Methods Clin Dev
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  • The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinsons disease. Zhao M et al., 2021 Aug, Cell Death Differ
    Read more
  • Protective effects of oridonin against cerebral ischemia/reperfusion injury by inhibiting the NLRP3 inflammasome activation. Jia Y et al., 2021 Aug, Tissue Cell
    Read more
  • Bone marrow mesenchymal stem cells upregulate PI3K/AKT pathway and down-regulate NF-kappaB pathway by secreting glial cell-derived neurotrophic factors to regulate microglial polarization and alleviate deafferentation pain in rats. Zhong Z et al., 2020 Sep, Neurobiol Dis
    Read more