More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Iba1 antibody [GT10312]

Iba1 antibody [GT10312]

GTX632426
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetAIF1
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    Iba1 antibody [GT10312]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT10312
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID199
  • Target name
    AIF1
  • Target description
    allograft inflammatory factor 1
  • Target synonyms
    AIF-1, IBA1, IRT-1, IRT1, allograft inflammatory factor 1, interferon gamma responsive transcript, ionized calcium-binding adapter molecule 1, protein G1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP55008
  • Protein Name
    Allograft inflammatory factor 1
  • Scientific Description
    This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Huang CC, Chiu HY, Lee PH, et al. Mitochondrial transplantation attenuates traumatic neuropathic pain, neuroinflammation, and apoptosis in rats with nerve root ligation. Mol Pain. 2023,19:17448069231210423. doi: 10.1177/17448069231210423
    Read this paper
  • Kwon H, Lee EH, Park SY, et al. Lactobacillus-derived extracellular vesicles counteract Aβ42-induced abnormal transcriptional changes through the upregulation of MeCP2 and Sirt1 and improve Aβ pathology in Tg-APP/PS1 mice. Exp Mol Med. 2023,55(9):2067-2082. doi: 10.1038/s12276-023-01084-z
    Read this paper
  • Zhou GF, Tang J, Ma YL, et al. ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation. Proc Natl Acad Sci U S A. 2023,120(22):e2220148120. doi: 10.1073/pnas.2220148120
    Read this paper
  • Sun R, Han R, McCornack C, et al. TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma. Sci Adv. 2023,9(19):eade3559. doi: 10.1126/sciadv.ade3559
    Read this paper
  • Yu H, Yu Q, Mi Y, et al. Hydrogen Sulfide Inhibited Sympathetic Activation in D-Galactose-Induced Aging Rats by Upregulating Klotho and Inhibiting Inflammation in the Paraventricular Nucleus. Biomedicines. 2023,11(2). doi: 10.3390/biomedicines11020566
    Read this paper
  • Sakai K, Sugano-Nakamura N, Mihara E, et al. Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions. Nat Biomed Eng. 2023,7(2):164-176. doi: 10.1038/s41551-022-00955-6
    Read this paper
  • Ding Z, Zhong Z, Wang J, et al. Inhibition of Dectin-1 Alleviates Neuroinflammatory Injury by Attenuating NLRP3 Inflammasome-Mediated Pyroptosis After Intracerebral Hemorrhage in Mice: Preliminary Study Results. J Inflamm Res. 2022,15:5917-5933. doi: 10.2147/JIR.S384020
    Read this paper
  • Tang M, Zhao S, Liu JX, et al. Paclitaxel induces cognitive impairment via necroptosis, decreased synaptic plasticity and M1 polarisation of microglia. Pharm Biol. 2022,60(1):1556-1565. doi: 10.1080/13880209.2022.2108064
    Read this paper
  • Cao Q, Luo S, Yao W, et al. Suppression of abnormal α-synuclein expression by activation of BDNF transcription ameliorates Parkinson's disease-like pathology. Mol Ther Nucleic Acids. 2022,29:1-15. doi: 10.1016/j.omtn.2022.05.037
    Read this paper
  • Fei X, Dou YN, Wang L, et al. Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage. J Neuroinflammation. 2022,19(1):67. doi: 10.1186/s12974-022-02428-8
    Read this paper

Datasheet

Download Datasheet

FAQ

Go to our frequently asked questions

Related products

Product group Antibodies
Biomatik
Aif1 Polyclonal AntibodyCAC07299
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
TargetAIF1
  • SizePrice
Product group Antibodies
Assay Genie
DBP AntibodyCAB15270
TargetAIF1
  • SizePrice
Anti-Iba1 Antibody
Product group Antibodies
Antibodies.com
Anti-Iba1 AntibodyA104332
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
  • SizePrice
Product group Antibodies
Biosynth
IBA1 antibody70R-21567
  • SizePrice
Formalin-fixed and paraffin embedded mouse spinal cord stained with AIF1 Polyclonal Antibody (bs-1363R) at 1:100 dilution. (a) Sham group; (b) Tumor group; (c) l-CDL 5 mg/kg group; (d) l-CDL 10 mg/kg group; (e) l-CDL 20 mg/kg group; (f) O&A 1&65 m/kg group (g) l-THP 20 mg/kg group. B Graph showing the mean fluorescence intensity for AIF1.
Product group Antibodies
References
Bioss
AIF1/Iba1 Polyclonal AntibodyBS-1363R
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetAIF1
  • SizePrice
Product group Antibodies
RayBiotech
Anti-AIF1 Antibody144-60080
ApplicationsWestern Blot
TargetAIF1
  • SizePrice
Figure 1. Western blot analysis of Iba1/AIF1 using anti-Iba1/AIF1 antibody (A01394). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human HEL whole cell lysates, Lane 2: human THP-1 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Iba1/AIF1 antigen affinity purified polyclonal antibody (Catalog # A01394) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Iba1/AIF1 at approximately 17 kDa. The expected band size for Iba1/AIF1 is at 17 kDa.
Product group Antibodies
Boster Bio
Anti-Iba1/AIF1 Antibody Picoband(r)A01394-CARRIER-FREE
ApplicationsWestern Blot, ImmunoHistoChemistry
TargetAIF1
  • SizePrice
Immunohistochemical staining of human cerebral cortex shows moderate cytoplasmic positivity in microglia.
Product group Antibodies
Atlas Antibodies
Anti-AIF1 AntibodyAMAB91671
ApplicationsImmunoHistoChemistry
ReactivityHuman
TargetAIF1
  • SizePrice
Product group Antibodies
Absolute Antibody
Anti-AIF1 [GT1-mAb1]AB03986-1.1
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA
TargetAIF1
  • SizePrice
Product group Antibodies
Everest Biotech
Goat anti-AIF1 / IBA1 (isoform 1 and 3), biotinylatedEB05419-B
ApplicationsWestern Blot, ELISA
TargetAIF1
  • SizePrice