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Iba1 antibody

GTX101495
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetAIF1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Iba1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.14 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID199
  • Target name
    AIF1
  • Target description
    allograft inflammatory factor 1
  • Target synonyms
    AIF-1, IBA1, IRT-1, IRT1, allograft inflammatory factor 1, interferon gamma responsive transcript, ionized calcium-binding adapter molecule 1, protein G1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP55008
  • Protein Name
    Allograft inflammatory factor 1
  • Scientific Description
    This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Tsai CM, Chang SF, Li CC, et al. Transcranial photobiomodulation (808 nm) attenuates pentylenetetrazole-induced seizures by suppressing hippocampal neuroinflammation, astrogliosis, and microgliosis in peripubertal rats. Neurophotonics. 2022,9(1):015006. doi: 10.1117/1.NPh.9.1.015006
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  • Jhan MK, Chen CL, Shen TJ, et al. Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus. Cells. 2021,10(11). doi: 10.3390/cells10113181
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  • Navarro-Sempere A, Martínez-Peinado P, Rodrigues AS, et al. The Health Hazards of Volcanoes: First Evidence of Neuroinflammation in the Hippocampus of Mice Exposed to Active Volcanic Surroundings. Mediators Inflamm. 2021,2021:5891095. doi: 10.1155/2021/5891095
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  • Ho MH, Yen CH, Hsieh TH, et al. CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury. Redox Biol. 2021,46:102067. doi: 10.1016/j.redox.2021.102067
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  • Sun XY, Li LJ, Dong QX, et al. Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer's disease. J Neuroinflammation. 2021,18(1):131. doi: 10.1186/s12974-021-02182-3
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  • Lhussiez V, Dubus E, Cesar Q, et al. Cohen Syndrome-Associated Cataract Is Explained by VPS13B Functions in Lens Homeostasis and Is Modified by Additional Genetic Factors. Invest Ophthalmol Vis Sci. 2020,61(11):18. doi: 10.1167/iovs.61.11.18
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  • Baskaran R, Lai CC, Li WY, et al. Characterization of striatal phenotypes in heterozygous Disc1 mutant mice, a model of haploinsufficiency. J Comp Neurol. 2020,528(7):1157-1172. doi: 10.1002/cne.24813
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  • Zhao Z, Fu J, Li S, et al. Neuroprotective Effects of Genistein in a SOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis. J Neuroimmune Pharmacol. 2019,14(4):688-696. doi: 10.1007/s11481-019-09866-x
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